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About Serene: Long Island Home Nursing Since 2009
Serene Home Nursing Agency provides personalized, professional home care across Long Island, including Suffolk County, Nassau County and Queens. Since 2009 we have delivered compassionate, dependable care tailored to the specific needs of each patient and family we serve.
We are a Licensed Home Care Services Agency, which means our nurses, home health aides and therapists bring care to patients in their own home. Our clients range from children with complex medical needs to adults managing a chronic illness and seniors who want to remain independent at home with the right assistance.
Experienced clinical supervisors and a rigorous caregiver screening process help keep every patient safe and supported.
Our Commitment to Patients and Families
Quality Care
Professional, dependable nursing care and home health services, planned around each patient's medical needs and supervised by registered nurses.
Availability
Our team is available 24/7 to give families guidance, answer questions and respond when care needs change.
Compassion
We treat every client with dignity and respect, so patients feel safe and family members have peace of mind about the care their loved one receives.
Experience You Can Trust
Our leadership and administrative team brings more than 100 years of combined experience in patient care, healthcare management, home health services and education. That experience shapes how we hire, train and supervise every caregiver.
Our quality assurance and clinical leadership teams, including management and a physician, work together to continuously improve patient care, safety and outcomes. Care plans are reviewed as needs change, and families can reach the team directly with concerns.

100+ Years
Combined Experience
Since 2009
Serving Long Island
3 Counties
Covered
Giving Back to Our Community
We are proud to support nonprofit organizations, healthcare initiatives, and community programs as part of our ongoing commitment to giving back across Long Island.
Through strong relationships with healthcare providers, community organizations, and local resources, we help connect patients and families with the support and care they need.

Meet Our Founder
Irene Manolias, RN — Founder & CEO
With more than 25 years of healthcare experience, Irene Maniolas, RN founded Serene Home Nursing Agency with a mission to provide compassionate, high-quality home care services throughout Long Island.
Known for her leadership, clinical expertise, and dedication to the community, Irene has built a trusted reputation as a healthcare professional and advocate for children and individuals with disabilities. She has organized fundraising initiatives and provided scholarships and awards to students and healthcare professionals who demonstrate leadership and community involvement.
From 2005 to 2016, Irene served as Director of Health Services for the Testaverde Foundation, supporting individuals with paralysis through access to essential equipment, services, and emotional support. She has also trained hundreds of nurses in advanced neurological techniques to help improve patient outcomes.
Her work has earned multiple recognitions, including the Platinum Professional Award for Outstanding Leadership in Healthcare (2014), Dan’s Papers Power List (2021), and the Schneps Media Healthcare Heroes Award (2021).
Today, Irene continues to oversee the care of pediatric, adult, and senior patients across Long Island while remaining deeply committed to delivering exceptional home care services to the community she has served throughout her career.
Recognitions & Awards



(2014)
(2021)
(2021)
